e_swartz

[www.modernmeadow.com](www.modernmeadow.com). lab grown leather for those interested

Memphis Meats say they will not sell a product that has been produced by way of use of animal sera in cell culture media formulations. I am aware that low-serum conditions actually promote satellite cell fusion and myotube formation, but what alternatives are being used to promote and maintain a symmetrically renewing satellite cell population in vitro?

Do you see a future where meat is derived from induced pluripotent stem cells, thus avoiding a muscle biopsy altogether?

dividing cells have a natural limit of cell divisions known as the Hayflick limit which is typically around 50 doublings. This can be avoided by creating an immortalized cell line through some genetic engineering tricks that allow for cells to bypass this limit. Whether or not an agency like the FDA would allow this is yet to be seen. In theory, induced pluripotent stem cells (which can divide indefinitely) could be used to derive meat as well. However, as a cell population doubles it has to replicate its DNA each time and thus the chance of introducing polymorphisms, deletions, insertions, or chromosomal duplications is possible. This matters more in the context of disease-related research as you don't want a messed up genetic background to interfere with your studies. It's possible that in the future there will be standardized meat-producing cell lines which have been proven to be most efficient or have the best taste/texture, etc.

Can you do another podcast with Dan Carlin?

yes, it would be possible